A colorimetric and fluorescent merocyanine-based probe for biological thiols.

نویسندگان

  • Shu-Ping Wang
  • Wu-Jian Deng
  • Dan Sun
  • Min Yan
  • Hong Zheng
  • Jin-Gou Xu
چکیده

A new "dual-mode" chromogenic and fluorescent turn-on probe (2) for the selective sensing of biological thiols is reported. In MeOH-H(2)O cosolvent at physiological pH 7.40 (MeOH-H(2)O = 3:7), biological thiols cleave the 2,4-dinitrobenzenesulfonyl group to release the chromo- and fluorophore merocyanine (3).

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 7 19  شماره 

صفحات  -

تاریخ انتشار 2009